@article {1307843,
	title = {Dementia prevalence and incidence in a federation of European Electronic Health Record databases: The European Medical Informatics Framework resource},
	journal = {Alzheimers Dement},
	volume = {14},
	number = {2},
	year = {2018},
	month = {2018 Feb},
	pages = {130-139},
	abstract = {INTRODUCTION: The European Medical Information Framework consortium has assembled electronic health record (EHR) databases for dementia research. We calculated dementia prevalence and incidence in 25 million persons from 2004 to~2012.

METHODS: Six EHR databases (three primary care and three secondary care) from five countries were interrogated. Dementia was ascertained by consensus harmonization of clinical/diagnostic codes. Annual period prevalences and incidences by age and gender were calculated and meta-analyzed.

RESULTS: The six databases contained 138,625 dementia cases. Age-specific prevalences were around 30\% of published estimates from community samples and incidences were around 50\%. Pooled prevalences had increased from 2004 to 2012 in all age groups but pooled incidences only after age 75~years. Associations with age and gender were stable over time.

DISCUSSION: The European Medical Information Framework initiative supports EHR data on unprecedented number of people with dementia. Age-specific prevalences and incidences mirror estimates from community samples in pattern at levels that are lower but increasing over time.},
	issn = {1552-5279},
	doi = {10.1016/j.jalz.2017.06.2270},
	author = {Perera, Gayan and Pedersen, Lars and Ansel, David and Alexander, Myriam and Arrighi, H Michael and Avillach, Paul and Foskett, Nadia and Gini, Rosa and Gordon, Mark F and Gungabissoon, Usha and Mayer, Miguel-Angel and Novak, Gerald and Rijnbeek, Peter and Trifir{\`o}, Gianluca and van der Lei, Johan and Visser, Pieter J and Stewart, Robert}
}
